Stress could have a negative impact both on your general health and oral health. Stress along with other psychological factors, such as anxiety, depression, and loneliness increases the risk of periodontal disease. Cortisol, also known as the stress hormone, is secreted by the adrenal glands and involved in many functions, including proper glucose metabolism, blood pressure regulation, insulin release for blood sugar maintenance, immune function, and inflammatory response. Scientists found that an increased levels of cortisol can lead to more destruction of the gums and bone due to periodontal diseases. People who are under extreme amounts of stress or suffering from depression may be more likely to disregard good oral hygiene. They may even take on new behaviors that could negatively impact their oral health, such as the use of nicotine, alcohol, or drugs, all of which can affect the teeth and gums. It is important to find healthy things that help relieve stress. A regular exercise routine can do wonders for relieving stress, as well as having a balanced nutritious diet and getting enough sleep. If you find it difficult to manage your stress you should see your physician. You should also make your dentist aware of your stress level so that he/she can make any necessary recommendations.